Items where Author is "Kumar, Shant"

Liu, Donghui, Kumar, Shant, Ashworth, Jason ORCID: https://orcid.org/0000-0001-7045-7899, Ali, Kamela, Fadel, Abdulmannan, Guo, Baoqiang and Slevin, Mark (2021) CD105 (Endoglin): A Potential Anticancer Therapeutic Inhibits Mitogenesis and Map Kinase Pathway Activation. Anticancer Research, 41 (3). pp. 1219-1229. ISSN 0250-7005

Slevin, Mark, Kumar, Patricia, Wang, Qiuyu, Kumar, Shant, Gaffney, John, Grau-Olivares, Marta and Krupinski, Jerzy (2008) New VEGF antagonists as possible therapeutic agents in vascular disease. Expert opinion on investigational drugs, 17 (9). pp. 1301-1314. ISSN 1354-3784

(2008) Atherothrombosis and plaque heterology: different location or a unique disease? Pathobiology, 75 (4). pp. 209-225. ISSN 1423-0291

Slevin, Mark, Ethirajan, Priya, Molki, Mohammed, Gaffney, John, Kumar, Shant, Kumar, Patricia and Krupinski, Jerzy (2008) Dynamin and perforin are associated with neovascularisation in advanced carotid plaques. Frontiers in Bioscience-Landmark, 13 (17). pp. 6515-6519. ISSN 1093-4715

(2008) The normal cellular prion protein and its possible role in angiogenesis. Frontiers in bioscience, 13 (17). pp. 6491-6500. ISSN 1093-4715

(2008) Leukaemia inhibitory factor is over-expressed by ischaemic brain tissue concomitant with reduced plasma expression following acute stroke. European journal of neurology, 15 (1). pp. 29-37. ISSN 1351-5101

Slevin, Mark, Grau-Olivares, Marta, Gaffney, John, Kumar, Patricia, Hussain, Sajjad, Kumar, Shant and Krupinski, Jerzy (2007) Does cyclic dependent kinase 5 play a significant role in determination of stroke outcome? Possible therapeutic implications. Central nervous system agents in medicinal chemistry, 7 (4). pp. 251-258. ISSN 1871-5249

(2007) A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion. BMC Neuroscience, 8 (1). ISSN 1471-2202

Li, Honggui, Wang, Qiuyu, Li, Hong Mei, Kumar, Shant, Parker, Craig J., Slevin, Mark and Kumar, Patricia (2007) PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN. Cancer letters, 253 (2). pp. 215-23. ISSN 0304-3835

Wang, Qiuyu, Kumar, Shant, Mitsios, Nicholas, Slevin, Mark and Kumar, Patricia (2007) Investigation of downstream target genes of PAX3c, PAX3e and PAX3g isoforms in melanocytes by microarray analysis. International journal of cancer, 120 (6). pp. 1223-1231. ISSN 0020-7136

(2007) Cellular prion protein is increased in the plasma and peri-infarcted brain tissue after acute stroke. Journal of Neuroscience Research, 85 (3). pp. 602-611. ISSN 0360-4012

(2007) Hyaluronan-mediated angiogenesis in vascular disease: uncovering RHAMM and CD44 receptor signaling pathways. Matrix biology, 26 (1). pp. 58-68. ISSN 0945-053X

(2007) Expression of cyclin-dependent kinase 5 mRNA and protein in the human brain following acute ischemic stroke. Brain pathology, 17 (1). pp. 11-23. ISSN 1015-6305

(2007) Expression of signaling molecules associated with apoptosis in human ischemic stroke tissue. Cell biochemistry and biophysics, 47 (1). pp. 73-86. ISSN 1085-9195

Mitsios, Nicholas, Gaffney, John, Kumar, Patricia, Krupinski, Jerzy, Kumar, Shant and Slevin, Mark (2006) Pathophysiology of acute ischaemic stroke : an analysis of common signalling mechanisms and identification of new molecular targets. Pathobiology, 73 (4). pp. 159-175. ISSN 1015-2008

(2006) A comparative study of neovascularisation in atherosclerotic plaques using CD31, CD105 and TGF beta 1. Pathobiology, 73 (4). pp. 192-197. ISSN 1423-0291

Slevin, Mark, Kumar, Patricia, Gaffney, John, Kumar, Shant and Krupinski, Jerzy (2006) Can angiogenesis be exploited to improve stroke outcome? Mechanisms and therapeutic potential. Clinical Science, 111 (3). pp. 171-83. ISSN 0143-5221

Wang, Qiuyu, Kumar, Shant, Slevin, Mark and Kumar, Patricia (2006) Functional analysis of alternative isoforms of the transcription factor PAX3 in melanocytes in vitro. Cancer research, 66 (17). pp. 8574-8580. ISSN 0008-5472

(2006) Changes in hyaluronan production and metabolism following ischaemic stroke in man. Brain, 129 (8). pp. 2158-2176. ISSN 0006-8950

(2006) Concomitant cell growth and differentiation are dependent on erbB1 and integrin activation in an autonomously surviving colon adenocarcinoma: involvement of autocrine amphiregulin secretion. Anticancer Research, 26 (4B). pp. 2769-2783. ISSN 0250-7005

Kumar, Shant, Letarte, M., McDonald, M. L. and Li, Chenggang (2005) Reduced endothelial secretion and plasma levels of transforming growth factor-beta1 in patients with hereditary hemorrhagic telangiectasia type 1. Cardiovascular Research, 68 (1). pp. 155-164. ISSN 0008-6363

(2005) Expression of basic fibroblast growth factor mRNA and protein in the human brain following ischaemic stroke. Angiogenesis, 8 (1). pp. 53-62. ISSN 0969-6970

Saka, Mohamad, Gaffney, John, Kumar, Patricia, Kumar, Shant and Slevin, Mark (2005) Changes in gene regulation and protein activation following acute ischaemic stroke in a rat middle cerebral artery occlusion model. [Conference or Workshop Item] (Unpublished)

Mitsios, Nicholas, Saka, Mohamad, Gaffney, John, Kumar, Patricia, Kumar, Shant and Slevin, Mark (2005) A microarray study of gene expression in human brain after ischaemic stroke: identification of novel genes and comparison with the rat middle cerebral artery occlusion model of ischaemic stroke. [Conference or Workshop Item] (Unpublished)

(2004) Overexpression of CD105 in rat myoblasts: role of CD105 in cell attachment, spreading and survival. International Journal of oncoogy, 25 (2). pp. 285-91. ISSN 1019-6439

(2004) CD105 inhibits transforming growth factor-beta-Smad3 signalling. Anticancer Research, 24 (3A). pp. 1337-1346. ISSN 0250-7005

Kumar, Shant, Costello, B., Li, Chenggang and Duff, S. (2004) Perfusion of 99Tcm-Labeled CD105 Mab into kidneys from patients with renal carcinoma suggests that CD105 is a promising vascular target. International journal of cancer, 109 (3). pp. 436-441. ISSN 1097-0215

Guo, Baoqiang, Kumar, Shant, Li, Chenggang, Slevin, Mark and Kumar, Patricia (2004) CD105 (Endoglin), apoptosis and stroke. Stroke, 35 (5). e94-e95. ISSN 0039-2499

(2004) Expression of PAX 3 alternatively spliced transcripts and identification of two new isoforms in human tumors of neural crest origin. International journal of cancer, 108 (2). pp. 314-320. ISSN 0020-7136

Slevin, Mark, Krupinski, Jerzy, Kumar, Patricia, Gaffney, John and Kumar, Shant (2004) Hyaluronan, angiogenesis and malignant disease. John Wiley.

Li, Chenggang, Issa, Razao, Kumar, Patricia, Hampson, Ian N., Lopez-Novoa, Jose M., Bernabeu, Carmelo and Kumar, Shant (2003) CD105 prevents apoptosis in hypoxic endothelial cells. Journal of Cell Science, 116 (13). pp. 2677-2685. ISSN 0021-9533

Wang, Qiuyu, Parker, Craig J., Kumar, Shant and Kumar, Patricia (2003) Functional analyses of alternative isoforms of PAX3 in melancytes. In: British Cancer Research Meeting 2003, 2nd-5th July 2003, Bournemouth, UK.

Kumar, Shant, Li, Chenggang, Gardy, R. and Seon, B. (2003) Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosis. British journal of cancer, 88 (9). pp. 1424-1431. ISSN 0306-9443

Mitsios, Nicholas, Gaffney, John, Krupinski, Jerzy, Kumar, Patricia, Kumar, Shant and Slevin, Mark (2003) Changes in gene regulation and associated protein expression after acute ischaemic stroke in man. In: 17th national meeting of the British Neuroscience Association, 13-16 April 2003, Harrogate, UK.

(2003) TNFα down-regulates CD105 expression in vascular endothelial cells: a comparative study with TGFß1. Anticancer Research, 23 (2B). pp. 1189-1196. ISSN 0250-7005

Slevin, Mark, Kumar, Shant and Gaffney, John (2002) Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses. Journal of biological chemistry, 277 (43). pp. 41046-41059. ISSN 0021-9258

Parker, Craig J., Shawcross, Susan G., Hart, Ian R., Kumar, Shant, MacKie, Rhona M., Sisely, Karen and Kumar, Patricia (2001) Expression of PAX3 spliced transcripts in human tumours of neural crest origin. Nature Publishing Group.

Slevin, Mark, Kumar, Shant, He, Xiaotong and Gaffney, John (1999) Physiological concentrations of gangliosides GM1, GM2 and GM3 differentially modify basic-fibroblast-growth-factor-induced mitogenesis and the associated signalling pathway in endothelial cells. International journal of cancer, 82 (3). pp. 412-23. ISSN 0020-7136

Issa, Razao, Krupinski, Jerzy, Bujny, Tomasz, Kumar, Shant, Kaluza, Jozef and Kumar, Patricia (1999) Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. Laboratory investigation, 79 (4). pp. 417-25. ISSN 0023-6837

(1998) The mutation status of PAX3 and p53 genes in medulloblastoma. Anticancer Research, 18 (2). pp. 849-854. ISSN 0250-7005

Deed, Richard, Rooney, Paul, Kumar, Patricia, Norton, John D., Smith, Julia, Freemont, Anthony J. and Kumar, Shant (1997) Early-response gene signalling is induced by angiogenic oligosaccharides of hyaluronan in endothelial cells. Inhibition by non-angiogenic, high-molecular-weight hyaluronan. International journal of cancer, 71 (2). pp. 251-6. ISSN 0020-7136

Krupinski, Jerzy, Issa, Razao, Bujny, Tomasz, Slevin, Mark, Kumar, Patricia, Kumar, Shant and Kaluza, Jozef (1997) A putative role for platelet-derived growth factor in angiogenesis and neuroprotection after ischemic stroke in humans. Stroke, 28 (3). pp. 564-573. ISSN 0039-2499