A new deep learning approach for the retinal hard exudates detection based on superpixel multi-feature extraction and patch-based CNN

Huang, Chenxi, Zong, Yongshuo, Ding, Yimin, Luo, Xin, Clawson, Kathy and Peng, Yonghong ORCID: https://orcid.org/0000-0002-5508-1819 (2021) A new deep learning approach for the retinal hard exudates detection based on superpixel multi-feature extraction and patch-based CNN. Neurocomputing, 452. pp. 521-533. ISSN 0925-2312

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Abstract

Diabetic Retinopathy (DR) is a severe complication of chronic diabetes causing significant visual deterioration and may lead to blindness with delay of being treated. Exudative diabetic maculopathy, a form of macular edema where hard exudates (HE) develop, is a frequent cause of visual deterioration in DR. The detection of HE comprises a significant role in the DR diagnosis. In this paper, an automatic exudates detection method based on superpixel multi-feature extraction and patch-based deep convolutional neural network is proposed. Firstly, superpixels, regarded as candidates, are generated on each resized image using the superpixel segmentation algorithm called Simple Linear Iterative Clustering (SLIC). Then, 25 features extracted from resized images and patches are generated on each feature. Patches are subsequently used to train a deep convolutional neural network, which distinguishes the hard exudates from the background. Experiments conducted on three publicly available datasets (DiaretDB1, e-ophtha EX and IDRiD) demonstrate that our proposed methodology achieved superior HE detection when compared with current state-of-art algorithms.