The challenge of New Psychoactive Substances - a technical update

Sutcliffe, Oliver ORCID: https://orcid.org/0000-0003-3781-7754, Creen, Conor, Raithelhuber, Martin and Tettey, Justice (2024) The challenge of New Psychoactive Substances - a technical update. Technical Report. United Nations, Vienna.

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Abstract

The challenge of New Psychoactive Substances – a technical update 2024 is an update of the UNODC publication “The challenge of new psychoactive substances, 2013”, which focuses on the new psychoactive substances (NPS) encountered on the market. The report is structured by effect groups of NPS with descriptions of mechanism of action, form/preparations, routes of administration and scheduled substances within each group. In addition, the content for each NPS group looks at substructural chemical classification and evolution through modification of core structures including effects of structural change on activity.