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    Efficacy of home-based physical activity interventions in patients with autoimmune rheumatic diseases: A systematic review and meta-analysis

    Sieczkowska, SM, Smaira, FI, Mazzolani, BC, Gualano, B, Roschel, H and Peçanha, T (2021) Efficacy of home-based physical activity interventions in patients with autoimmune rheumatic diseases: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism, 51 (3). pp. 576-587. ISSN 0049-0172

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    Abstract

    Introduction: Physical activity (PA) has been receiving increasing interest in recent years as an adjuvant therapy for autoimmune rheumatic disease (ARDs), but there is scarce information about the efficacy of home-based PA for patients with ARDs. Objective: To perform a systematic review and meta-analysis on the efficacy of home-based physical activity (PA) interventions in improving health-related quality of life, functional capacity, pain, and disease activity in patients with ARDs. Methods: Searches were performed in PubMed, Web of Science, Scopus, Cochrane, CINAHL database and Sport Discus. Trials were considered eligible if they included a home-based physical activity intervention. The population included adults with autoimmune rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, idiopathic inflammatory myopathies, systemic sclerosis and ankylosing spondylitis), comparisons included non-physical activity control or centre-based interventions (i.e., interventions performed on a specialized exercise centre) and the outcomes were quality of life, pain, functional capacity, disease activity and inflammation. Results: Home-based physical activity improved quality of life (p<0.01; g = 0.69; IC95%, 0.61 to 1.07) and functional capacity (p = 0.04; g = - 0.51; IC95%, -0.86; -0.16), and reduced disease activity (p = 0.03; g = - 0.60; IC95%, -1.16; -0.04) and pain (p = 0.01; g = -1.62; IC95%, -2.94 to -0.31) compared to the non-physical activity control condition. Additionally, home-based physical activity interventions were as effective as centre-based interventions for all investigated outcomes. Conclusion: Home-based PA is an efficacious strategy to improve disease control and aleviate symptoms in ARD.

    Item Type: Article
    Peer-reviewed: Yes
    Date Deposited: 27 Jun 2022 10:39
    Publisher: Elsevier
    Additional Information: This is an Author Accepted Manuscript of an article published in Seminars in Arthritis and Rheumatism by Elsevier.
    Divisions: Faculties > Science and Engineering
    Research Centres > Musculoskeletal Sciences & Sport Medicine
    Subject terms: Science & Technology, Life Sciences & Biomedicine, Rheumatology, Exercise, Pain, Fitness, QUALITY-OF-LIFE, GROUP-BASED EXERCISE, ANKYLOSING-SPONDYLITIS, LUPUS-ERYTHEMATOSUS, ARTHRITIS METAANALYSIS, AEROBIC EXERCISE, AQUATIC EXERCISE, PAIN, BARRIERS, PROGRAM, Humans, Spondylitis, Ankylosing, Arthritis, Rheumatoid, Exercise, Exercise Therapy, Quality of Life, Adult, Exercise, Fitness, Pain, Rheumatology, Adult, Arthritis, Rheumatoid, Exercise, Exercise Therapy, Humans, Quality of Life, Spondylitis, Ankylosing, 1103 Clinical Sciences, 1117 Public Health and Health Services, Arthritis & Rheumatology
    URI: https://e-space.mmu.ac.uk/id/eprint/629956
    DOI: https://doi.org/10.1016/j.semarthrit.2021.04.004
    ISSN 0049-0172
    e-ISSN 1532-866X

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