Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability

Hampton, Thomas H, Thomas, Devin, van der Gast, Christopher ORCID: https://orcid.org/0000-0003-1101-4048, O’Toole, George A and Stanton, Bruce A (2021) Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability. Microbiology Spectrum, 9 (1). ISSN 2165-0497

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Abstract

While much research supports a polymicrobial view of the CF airway, one in which the community is seen as the pathogenic unit, only controlled experiments using model bacterial communities can unravel the mechanistic role played by different communities. This report uses a large data set to identify a small number of communities as a starting point in the development of tractable model systems.