DNA Methylation in Stroke. Update of Latest Advances

Krupinski, J, Carrera, C, Muiño, E, Torres, N, Al-Baradie, R, Cullell, N and Fernandez-Cadenas, I (2018) DNA Methylation in Stroke. Update of Latest Advances. Computational and Structural Biotechnology Journal, 16. pp. 1-5. ISSN 2001-0370

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Official URL: http://journals.sfu.ca/rncsb/index.php/csbj

Abstract

© 2017 The Authors. Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.

Item Type:	Article
Peer-reviewed:	Yes
Date Deposited:	22 Jun 2018 11:48
Publisher:	Research Network of Computational and Structural Biotechnology
Additional Information:	This is an Open Access article published in Computational and Structural Biotechnology Journal, published by Research Network of Computational and Structural Biotechnology, copyright The Author(s).
Divisions:	Faculties > Science and Engineering Research Centres > Centre for Bioscience
Subject terms:	EWAs, Epigenetics, GWAs, Genetics, Stroke
URI:	https://e-space.mmu.ac.uk/id/eprint/620888
DOI:	https://doi.org/10.1016/j.csbj.2017.12.001
ISSN	2001-0370

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