A Design Method for FES Bone Health Therapy in SCI.

Andrews, B, Shippen, J, Armengol, M, Gibbons, R, Holderbaum, W and Harwin, W (2016) A Design Method for FES Bone Health Therapy in SCI. European Journal of Translational Myology, 26 (4). pp. 297-300. ISSN 2037-7452

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Abstract

FES assisted activities such as standing, walking, cycling and rowing induce forces within the leg bones and have been proposed to reduce osteoporosis in spinal cord injury (SCI). However, details of the applied mechanical stimulus for osteogenesis is often not reported. Typically, comparisons of bone density results are made after costly and time consuming clinical trials. These studies have produced inconsistent results and are subject to sample size variations. Here we propose a design process that may be used to predict the clinical outcome based on biomechanical simulation and mechano-biology. This method may allow candidate therapies to be optimized and quantitatively compared. To illustrate the approach we have used data obtained from a rower with complete paraplegia using the RowStim (III) system.

Item Type:	Article
Peer-reviewed:	Yes
Date Deposited:	19 Apr 2018 11:41
Publisher:	PAGEPress
Additional Information:	This is an Open Access article published in European Journal of Translational Myology, published by PAGEPress, copyright The Author(s).
Divisions:	Faculties > Science and Engineering
Subject terms:	FES, FES rowing, bone stress, osteoporosis, spinal cord injury
URI:	https://e-space.mmu.ac.uk/id/eprint/620340
DOI:	https://doi.org/10.4081/ejtm.2016.6419
ISSN	2037-7452

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