Modulation of Innate and Adaptive Immune Responses by Arabinoxylans

Fadel, A, Plunkett, A, Li, W, Gyamfi, V, Nyaranga, R, Fadel, F, Dakak, S, Salmon, Y, Ashworth, J and Ranneh, Y (2018) Modulation of Innate and Adaptive Immune Responses by Arabinoxylans. Journal of Food Biochemistry, 42 (2). e12473. ISSN 0145-8884

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Abstract

Humans are exposed to harmful pathogens and a wide range of noxious substances every day. The immune system reacts to, and destroys, these pathogens and harmful substances. The immune system is composed of innate and adaptive immunity, which liaise to protect the host and maintain health. Foods, especially cereals, have been reported to modulate the immune response. Arabinoxylans are nonstarch polysaccharides that have been shown to possess immune-modulatory activities. This review article discusses the fundamentals of the immune system and provides an overview of the immunomodulatory potential of arabinoxylans in conjunction with their structural characteristics and proposed similarities with lipopolysaccharides.

Item Type:	Article
Peer-reviewed:	Yes
Date Deposited:	08 Feb 2018 10:19
Publisher:	Wiley
Additional Information:	This is an Author Accepted Manuscript of a paper accepted for publication in Journal of Food Biochemistry, published by and copyright Wiley.
Divisions:	Faculties > Health and Education Faculties > Science and Engineering
Subject terms:	Arabinoxylans, lipopolysaccharides, innate immunity, adaptive immunity, nitric oxide, Toll-like receptor, 0908 Food Sciences, Food Science
URI:	https://e-space.mmu.ac.uk/id/eprint/619945
DOI:	https://doi.org/10.1111/jfbc.12473
ISSN	0145-8884

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