Application of Ultrasonic Waves for Non-Invasive Detection and Treatment of Thrombosis

Karimian, Shokrollah and Karimian, Noushin (2024) Application of Ultrasonic Waves for Non-Invasive Detection and Treatment of Thrombosis. In: Proceedings of the Annual British Conference on Non-Destructive Testing, pp. 22-31. Presented at 61st Annual British Conference on Non-Destructive Testing, September 2-5, 2024, Telford, United Kingdom.

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Abstract

This research paper introduces a non-invasive approach for detecting and treating thrombosis through the use of ultrasonic waves to address blood clotting within blood vessels. Thrombosis, characterised by restricted blood flow due to clot formation, represents a significant contributor to conditions such as stroke and heart attacks. It is worth noting that in 2019, an estimated number of 17.9 million people died from Cardiovascular Diseases (CVDs), constituting approximately 32% of all global fatalities. Of this staggering figure, 85% of deaths were attributed to heart attacks and strokes. Consequently, the development of methods for its detection and treatment proves paramount importance. To achieve this, in-vitro tests were conducted on human blood clot tissue. Ultrasound waves of varying frequencies and intensities were irradiated over variable time intervals using timed pulses and continuous waves (CW). The outcome was validated through the examination of ultrasound images and the comparison of irradiated samples with the reference pattern. Additionally, disparities in the molecular structure of the tissue and clot walls were observed under the microscope. Consequently, the findings of this research substantiate that the proposed method offers a viable non-invasive alternative for thrombosis elimination and stroke prevention.