e-space
Manchester Metropolitan University's Research Repository

    Recent advances on the catalytic asymmetric allylic α-alkylation of carbonyl derivatives using free allylic alcohols

    Alonso, Diego A ORCID logoORCID: https://orcid.org/0000-0002-9069-1188, Maciá, Beatriz ORCID logoORCID: https://orcid.org/0000-0001-5148-0516, Pastor, Isidro M ORCID logoORCID: https://orcid.org/0000-0002-8271-0641 and Baeza, Alejandro ORCID logoORCID: https://orcid.org/0000-0002-6230-1162 (2024) Recent advances on the catalytic asymmetric allylic α-alkylation of carbonyl derivatives using free allylic alcohols. ACS Organic and Inorganic Au, 4 (3). pp. 269-286. ISSN 2694-247X

    [img]
    Preview
    Published Version
    Available under License Creative Commons Attribution Non-commercial No Derivatives.

    Download (4MB) | Preview

    Abstract

    During the last years, the development of more sustainable and straightforward methodologies to minimize the generation of waste organic substances has acquired high importance within synthetic organic chemistry. Therefore, it is not surprising that many efforts are devoted to ameliorating already well-known successful methodologies, that is, the case of the asymmetric allylic allylation reaction of carbonyl compounds. The use of free alcohols as alkylating agents in this transformation represents a step forward in this sense since it minimizes waste production and the substrate manipulation. In this review, we aim to gather the most recent methodologies describing this strategy by paying special attention to the reaction mechanisms, as well as their synthetic applications.

    Impact and Reach

    Statistics

    Activity Overview
    6 month trend
    106Downloads
    6 month trend
    214Hits

    Additional statistics for this dataset are available via IRStats2.

    Altmetric

    Repository staff only

    Edit record Edit record