A clinical review of antidepressants, their sexual side-effects, post-SSRI sexual dysfunction, and serotonin syndrome

Marks, Stephen ORCID: https://orcid.org/0000-0003-0832-853X (2023) A clinical review of antidepressants, their sexual side-effects, post-SSRI sexual dysfunction, and serotonin syndrome. British Journal of Nursing, 32 (14). pp. 678-682. ISSN 0142-0372

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Official URL: https://doi.org/10.12968/bjon.2023.32.14.678

Abstract

Depression and anxiety are common, with one in six people experiencing symptoms in any given week. Of these people, 8.32 million are prescribed antidepressants. People living with HIV are likely to experience psychiatric disorder, with one in three experiencing depression and anxiety, and being at greater risk of developing post-traumatic stress disorder. Sexual side-effects of psychotropic medication are very common, cause distress, and can persist even after the medication has been withdrawn. Antidepressants are powerful drugs and can have severe interactions with many other substances. This article seeks to raise awareness of sexual side-effects of psychotropic medications and draw attention to ethical issues related to post selective serotonin reuptake inhibitor sexual dysfunction (PSSD). Additional risk factors and interactions between psychotropic medications and recreational drugs are identified. Recommendations are made to improve care and clinical outcomes through the development of therapeutic alliances.

Item Type:	Article (Article)
Peer-reviewed:	Yes
Date Deposited:	26 Oct 2023 12:45
Publisher:	Mark Allen Healthcare
Additional Information:	This document is the Accepted Manuscript version of a Published Work that appeared in final form in British Journal of Nursing, copyright © MA Healthcare, after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.12968/bjon.2023.32.14.678.
Divisions:	Faculties > Health and Education
Subject terms:	Humans, Serotonin Syndrome, Antidepressive Agents, Sexual Behavior, Sexual Dysfunction, Physiological, Drug-Related Side Effects and Adverse Reactions, Selective Serotonin Reuptake Inhibitors, Antidepressants, Chemsex, Depression, Erectile dysfunction, HIV, Mental health/illness, PSSD, Recreational drugs, SSRIs, Serotonin, Serotonin syndrome, Sexual dysfunction, Humans, Serotonin Syndrome, Antidepressive Agents, Sexual Behavior, Sexual Dysfunction, Physiological, Selective Serotonin Reuptake Inhibitors, Drug-Related Side Effects and Adverse Reactions, 1110 Nursing
URI:	https://e-space.mmu.ac.uk/id/eprint/632844
DOI:	https://doi.org/10.12968/bjon.2023.32.14.678
ISSN	0142-0372
e-ISSN	2052-2819

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