e-space
Manchester Metropolitan University's Research Repository

    A scoping review on quality assessment tools used in systematic reviews and meta-analysis of real world studies

    Gebrye, Tadesse ORCID logoORCID: https://orcid.org/0000-0001-7976-2013, Fatoye, Francis ORCID logoORCID: https://orcid.org/0000-0002-3502-3953, Mbada, Chidozie ORCID logoORCID: https://orcid.org/0000-0003-3666-7432 and Hakimi, Zalmai (2023) A scoping review on quality assessment tools used in systematic reviews and meta-analysis of real world studies. Rheumatology International, 43 (9). pp. 1573-1581. ISSN 0172-8172

    [img]
    Preview
    Published Version
    Available under License Creative Commons Attribution.

    Download (483kB) | Preview

    Abstract

    Background: Risk of bias tools are important in identifying inherent methodical flaws and for generating evidence in studies involving systematic reviews (SRs) and meta-analyses (MAs), hence the need for sensitive and study-specific tools. This study aimed to review quality assessment (QA) tools used in SRs and MAs involving real world data. Methods: Electronic databases involving PubMed, Allied and Complementary Medicine Database, Cumulated Index to Nursing and Allied Health Literature, and MEDLINE were searched for SRs and MAs involving real world data. Search was delimited to articles published in English, and between inception to 20th of November 2022 following the SRs and MAs extension for scoping checklist. Result: Sixteen articles on real world data published between 2016 and 2021 that reported their methodological quality met the inclusion criteria. Seven of these articles were observational studies, while the others were of interventional type. Overall, 16 QA tools were identified. Except one, all the QA tools employed in SRs and MAs involving real world data are generic, and only three of these were validated. Conclusions: Generic QA tools are mostly used for real-world data SRs and MAs, while no validated and reliable specific tool currently exist. Thus, there is need for a standardized and specific QA tool of SRs and MAs for real world data.

    Impact and Reach

    Statistics

    Activity Overview
    6 month trend
    112Downloads
    6 month trend
    60Hits

    Additional statistics for this dataset are available via IRStats2.

    Altmetric

    Repository staff only

    Edit record Edit record