e-space
Manchester Metropolitan University's Research Repository

    Comparison of the effect of MFAT and MFAT + PRP on treatment of hip osteoarthritis : an observational, intention-to-treat study at one year

    Heidari, N, Slevin, M ORCID logoORCID: https://orcid.org/0000-0003-3767-4861, Zeinolabediny, Y, Meloni, D, Olgiati, S, Wilson, A, Noorani, A and Azamfirei, L (2022) Comparison of the effect of MFAT and MFAT + PRP on treatment of hip osteoarthritis : an observational, intention-to-treat study at one year. Journal of Clinical Medicine, 11 (4). p. 1056.

    [img]
    Preview
    Published Version
    Available under License Creative Commons Attribution.

    Download (27MB) | Preview

    Abstract

    Hip osteoarthritis (OA) is a major contributor to reduced quality of life and concomitant disability associated with lost working life months. Intra-articular injection of various biological materials has shown promise in alleviating symptoms and potentially slowing down the degenerative process. Here, we compared the effects of treatment of a cohort of 147 patients suffering from grade 1–4 hip OA; with either micro-fragmented adipose tissue (MFAT), or a combination of MFAT with platelet-rich plasma (PRP). We found significant improvements in both the visual analogue score for pain (VAS) and Oxford hip score (OHS) that were similar for both treatments with over 60% having an improvement in the VAS score of 20 points or more. These results suggest a positive role for intra-articular injection of MFAT + PRP as a treatment for hip osteoarthritis which may be important particularly in low body mass index (BMI) patients where the difficulty in obtaining sufficient MFAT for treatment could be offset by using this combination of biologicals.

    Impact and Reach

    Statistics

    Activity Overview
    6 month trend
    25Downloads
    6 month trend
    45Hits

    Additional statistics for this dataset are available via IRStats2.

    Altmetric

    Actions (login required)

    View Item View Item