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A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis.

Palma-Barqueros, Verónica and Crescente, Marilena and de la Morena, María Eugenia and Chan, Melissa V and Almarza, Elena and Revilla, Nuria and Bohdan, Natalia and Miñano, Antonia and Padilla, José and Allan, Harriet E and Maffucci, Tania and Edin, Matthew L and Zeldin, Darryl C and Mesa-Nuñez, Cristina and Damian, Carlos and Marín-Quilez, Ana and Benito, Rocío and Martínez-Martínez, Irene and Bermejo, Nuria and Casas-Aviles, Ignacio and Rodríguez-Alen, Agustín and González-Porras, José R and Hernández-Rivas, Jesús María and Vicente, Vicente and Corral, Javier and Lozano, María L and Warner, Timothy D and Bastida, José María and Rivera, José (2020) A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis. American Journal of Hematology, 96 (3). E83-E88. ISSN 0361-8609

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