The effects of vitamin C and E on exercise-induced physiological adaptations: a systematic review and Meta-analysis of randomized controlled trials

Clifford, Tom, Jeffries, Owen, Stevenson, Emma J and Davies, Kelly A Bowden (2019) The effects of vitamin C and E on exercise-induced physiological adaptations: a systematic review and Meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition, 60 (21). pp. 3669-3679. ISSN 0007-9006

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Official URL: https://www.tandfonline.com/doi/full/10.1080/10408...

Abstract

We conducted a systematic review and meta-analysis of randomized controlled trials examining the effect of vitamin C and/or E on exercise-induced training adaptations. Medline, Embase and SPORTDiscus databases were searched for articles from inception until June 2019. Inclusion criteria was studies in adult humans where vitamin C and/or E had to be consumed alongside a supervised exercise training program of ≥4 weeks. Nine trials were included in the analysis of aerobic exercise adaptations and nine for resistance training (RT) adaptations. Vitamin C and/or E did not attenuate aerobic exercise induced improvements in maximal aerobic capacity (V̇ O2max) (SMD −0.14, 95% CI: −0.43 to 0.15, P = 0.35) or endurance performance (SMD −0.01, 95% CI: −0.38 to 0.36, P = 0.97). There were also no effects of these supplements on lean mass and muscle strength following RT (SMD −0.07, 95% CI: −0.36 to 0.23, P = 0.67) and (SMD −0.15, 95% CI: −0.16 to 0.46, P = 0.35), respectively. There was also no influence of age on any of these outcomes (P > 0.05). These findings suggest that vitamin C and/or E does not inhibit exercise-induced changes in physiological function. Studies with larger sample sizes and adequate power are still required.

Item Type:	Article
Peer-reviewed:	Yes
Date Deposited:	10 Jun 2021 10:10
Publisher:	Taylor & Francis
Additional Information:	“This is an Accepted Manuscript of an article published by Taylor & Francis in Critical Reviews in Food Science and Nutrition on 18/12/2019, available online: http://www.tandfonline.com/10.1080/10408398.2019.1703642.”
Divisions:	Faculties > Science and Engineering Research Centres > Musculoskeletal Sciences & Sport Medicine
Subject terms:	Science & Technology, Life Sciences & Biomedicine, Food Science & Technology, Nutrition & Dietetics, Antioxidant, vitamin, skeletal muscle, endurance performance, resistance training, ANTIOXIDANT SUPPLEMENTATION, RESISTANCE EXERCISE, MUSCLE, PERFORMANCE, SPORTS, MASS, Science & Technology, Life Sciences & Biomedicine, Food Science & Technology, Nutrition & Dietetics, Antioxidant, vitamin, skeletal muscle, endurance performance, resistance training, ANTIOXIDANT SUPPLEMENTATION, RESISTANCE EXERCISE, MUSCLE, PERFORMANCE, SPORTS, MASS, Humans, Ascorbic Acid, Exercise, Adaptation, Physiological, Dietary Supplements, Adult, Randomized Controlled Trials as Topic, Antioxidant, endurance performance, resistance training, skeletal muscle, vitamin, Adaptation, Physiological, Adult, Ascorbic Acid, Dietary Supplements, Exercise, Humans, Randomized Controlled Trials as Topic, 0702 Animal Production, 0908 Food Sciences, 1111 Nutrition and Dietetics, Nutrition & Dietetics
URI:	https://e-space.mmu.ac.uk/id/eprint/627933
DOI:	https://doi.org/10.1080/10408398.2019.1703642
ISSN	0007-9006
e-ISSN	1549-7852

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