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The M-CAT's out of the bag: A paper-based microfluidic immunoassay for the rapid detection of mephedrone

Pearson, C and Sutcliffe, OB and Shaw, KJ (2016) The M-CAT's out of the bag: A paper-based microfluidic immunoassay for the rapid detection of mephedrone. In: The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), 09 October 2016 - 13 October 2016, Dublin, Ireland.

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Abstract

This paper reports a paper-based microfluidic competitive immunoassay for the detection of mephedrone, a new psychoactive substance (NPS). Using the proposed system, limits of detection of 4.078 μg mL-1 and 1.597 μg mL-1 for aqueous mephedrone and spiked urine samples, respectively, were obtained, with these values enabling the detection of clinically relevant concentrations of mephedrone. The proposed device has the opportunity to provide rapid, on-site testing, within either a forensic or clinical setting, for NPSs.

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