An arsenal of magnetic nanoparticles; Perspectives in the treatment of cancer

Karponis, D, Azzawi, M and Seifalian, A (2016) An arsenal of magnetic nanoparticles; Perspectives in the treatment of cancer. Nanomedicine, 11 (16). pp. 2215-2232. ISSN 1743-5889

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Official URL: http://www.futuremedicine.com/loi/nnm

Abstract

Nanomedicine is an emerging field, which constitutes a new direction in the treatment of cancer. Magnetic nanoparticles (MNPs) can circumvent vascular tissue to concentrate at the site of the tumor. Under the influence of an external, alternating magnetic field, MNPs generate high temperatures within the tumor and ablate malignant cells while inflicting minimal damage to healthy host tissue. Due to their theranostic properties, they constitute a promising candidate for the treatment of cancer. A critical review of the type, size and therapeutic effect of different MNPs is presented, following an appraisal of the literature in the last 5 years. This is a multibillion dollar industry, with a few studies moving to clinical trials within the next 5 years.

Item Type:	Article
Peer-reviewed:	Yes
Date Deposited:	29 Sep 2016 14:26
Publisher:	Future Medicine Group
Additional Information:	This is an author accepted manuscript of a paper accepted for publication in Nanomedicine, published by and copyright Future Medicine Group.
Divisions:	Faculties > Science and Engineering
Subject terms:	breast cancer, cancer, hyperthermia, iron nanoparticles, lung cancer, magnetic nanoparticles, nanomaterial, nanotechnology, superparamagnetic nanoparticles, Nanomedicine, Magnetic, Nanoscience & Nanotechnology, 1004 Medical Biotechnology, 1007 Nanotechnology
URI:	https://e-space.mmu.ac.uk/id/eprint/617202
DOI:	https://doi.org/10.2217/nnm-2016-0113
ISSN	1743-5889

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