e-space
Manchester Metropolitan University's Research Repository

    The ACE gene and muscle performance

    Williams, Alun G., Rayson, Mark P., Jubb, Mick, World, Michael, Woods, David R., Hayward, Marianne, Martin, Jason, Humphries, Steven E. and Montgomery, Hugh E. (2000) The ACE gene and muscle performance. Nature, 403. p. 614. ISSN 0028-0836

    File not available for download.

    Abstract

    Angiotensin-converting enzyme in human skeletal muscle1 can be encoded by either of two variants of the ACE gene2, one of which carries an insertion of 287 base pairs. This longer allele gives rise to lower enzyme activity2, and is associated with enhanced endurance performance3 and an anabolic response to intense exercise training4. Here we examine training-related changes in the mechanical efficiency of human skeletal muscle (energy used per unit power output) and find that the presence of this ACE allele confers an enhanced mechanical efficiency in trained muscle.

    Impact and Reach

    Statistics

    Activity Overview
    6 month trend
    0Downloads
    6 month trend
    483Hits

    Additional statistics for this dataset are available via IRStats2.

    Altmetric

    Repository staff only

    Edit record Edit record