Items where Author is "Kumar, Shant"
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Liu, Donghui, Kumar, Shant, Ashworth, Jason ORCID: https://orcid.org/0000-0001-7045-7899, Ali, Kamela, Fadel, Abdulmannan, Guo, Baoqiang and Slevin, Mark (2021) CD105 (Endoglin): A Potential Anticancer Therapeutic Inhibits Mitogenesis and Map Kinase Pathway Activation. Anticancer Research, 41 (3). pp. 1219-1229. ISSN 0250-7005
Slevin, Mark, Kumar, Patricia, Wang, Qiuyu, Kumar, Shant, Gaffney, John, Grau-Olivares, Marta and Krupinski, Jerzy (2008) New VEGF antagonists as possible therapeutic agents in vascular disease. Expert opinion on investigational drugs, 17 (9). pp. 1301-1314. ISSN 1354-3784
Slevin, Mark, Ethirajan, Priya, Molki, Mohammed, Gaffney, John, Kumar, Shant, Kumar, Patricia and Krupinski, Jerzy (2008) Dynamin and perforin are associated with neovascularisation in advanced carotid plaques. Frontiers in Bioscience-Landmark, 13 (17). pp. 6515-6519. ISSN 1093-4715
Slevin, Mark, Grau-Olivares, Marta, Gaffney, John, Kumar, Patricia, Hussain, Sajjad, Kumar, Shant and Krupinski, Jerzy (2007) Does cyclic dependent kinase 5 play a significant role in determination of stroke outcome? Possible therapeutic implications. Central nervous system agents in medicinal chemistry, 7 (4). pp. 251-258. ISSN 1871-5249
Li, Honggui, Wang, Qiuyu, Li, Hong Mei, Kumar, Shant, Parker, Craig J., Slevin, Mark and Kumar, Patricia (2007) PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN. Cancer letters, 253 (2). pp. 215-23. ISSN 0304-3835
Wang, Qiuyu, Kumar, Shant, Mitsios, Nicholas, Slevin, Mark and Kumar, Patricia (2007) Investigation of downstream target genes of PAX3c, PAX3e and PAX3g isoforms in melanocytes by microarray analysis. International journal of cancer, 120 (6). pp. 1223-1231. ISSN 0020-7136
Mitsios, Nicholas, Gaffney, John, Kumar, Patricia, Krupinski, Jerzy, Kumar, Shant and Slevin, Mark (2006) Pathophysiology of acute ischaemic stroke : an analysis of common signalling mechanisms and identification of new molecular targets. Pathobiology, 73 (4). pp. 159-175. ISSN 1015-2008
Slevin, Mark, Kumar, Patricia, Gaffney, John, Kumar, Shant and Krupinski, Jerzy (2006) Can angiogenesis be exploited to improve stroke outcome? Mechanisms and therapeutic potential. Clinical Science, 111 (3). pp. 171-83. ISSN 0143-5221
Wang, Qiuyu, Kumar, Shant, Slevin, Mark and Kumar, Patricia (2006) Functional analysis of alternative isoforms of the transcription factor PAX3 in melanocytes in vitro. Cancer research, 66 (17). pp. 8574-8580. ISSN 0008-5472
Kumar, Shant, Letarte, M., McDonald, M. L. and Li, Chenggang (2005) Reduced endothelial secretion and plasma levels of transforming growth factor-beta1 in patients with hereditary hemorrhagic telangiectasia type 1. Cardiovascular Research, 68 (1). pp. 155-164. ISSN 0008-6363
Kumar, Shant, Costello, B., Li, Chenggang and Duff, S. (2004) Perfusion of 99Tcm-Labeled CD105 Mab into kidneys from patients with renal carcinoma suggests that CD105 is a promising vascular target. International journal of cancer, 109 (3). pp. 436-441. ISSN 1097-0215
Guo, Baoqiang, Kumar, Shant, Li, Chenggang, Slevin, Mark and Kumar, Patricia (2004) CD105 (Endoglin), apoptosis and stroke. Stroke, 35 (5). e94-e95. ISSN 0039-2499
Li, Chenggang, Issa, Razao, Kumar, Patricia, Hampson, Ian N., Lopez-Novoa, Jose M., Bernabeu, Carmelo and Kumar, Shant (2003) CD105 prevents apoptosis in hypoxic endothelial cells. Journal of Cell Science, 116 (13). pp. 2677-2685. ISSN 0021-9533
Kumar, Shant, Li, Chenggang, Gardy, R. and Seon, B. (2003) Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosis. British journal of cancer, 88 (9). pp. 1424-1431. ISSN 0306-9443
Slevin, Mark, Kumar, Shant and Gaffney, John (2002) Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses. Journal of biological chemistry, 277 (43). pp. 41046-41059. ISSN 0021-9258
Slevin, Mark, Kumar, Shant, He, Xiaotong and Gaffney, John (1999) Physiological concentrations of gangliosides GM1, GM2 and GM3 differentially modify basic-fibroblast-growth-factor-induced mitogenesis and the associated signalling pathway in endothelial cells. International journal of cancer, 82 (3). pp. 412-23. ISSN 0020-7136
Issa, Razao, Krupinski, Jerzy, Bujny, Tomasz, Kumar, Shant, Kaluza, Jozef and Kumar, Patricia (1999) Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. Laboratory investigation, 79 (4). pp. 417-25. ISSN 0023-6837
Deed, Richard, Rooney, Paul, Kumar, Patricia, Norton, John D., Smith, Julia, Freemont, Anthony J. and Kumar, Shant (1997) Early-response gene signalling is induced by angiogenic oligosaccharides of hyaluronan in endothelial cells. Inhibition by non-angiogenic, high-molecular-weight hyaluronan. International journal of cancer, 71 (2). pp. 251-6. ISSN 0020-7136
Krupinski, Jerzy, Issa, Razao, Bujny, Tomasz, Slevin, Mark, Kumar, Patricia, Kumar, Shant and Kaluza, Jozef (1997) A putative role for platelet-derived growth factor in angiogenesis and neuroprotection after ischemic stroke in humans. Stroke, 28 (3). pp. 564-573. ISSN 0039-2499
Conference or Workshop Item
Saka, Mohamad, Gaffney, John, Kumar, Patricia, Kumar, Shant and Slevin, Mark (2005) Changes in gene regulation and protein activation following acute ischaemic stroke in a rat middle cerebral artery occlusion model. [Conference or Workshop Item] (Unpublished)
Mitsios, Nicholas, Saka, Mohamad, Gaffney, John, Kumar, Patricia, Kumar, Shant and Slevin, Mark (2005) A microarray study of gene expression in human brain after ischaemic stroke: identification of novel genes and comparison with the rat middle cerebral artery occlusion model of ischaemic stroke. [Conference or Workshop Item] (Unpublished)
Wang, Qiuyu, Parker, Craig J., Kumar, Shant and Kumar, Patricia (2003) Functional analyses of alternative isoforms of PAX3 in melancytes. In: British Cancer Research Meeting 2003, 2nd-5th July 2003, Bournemouth, UK.
Mitsios, Nicholas, Gaffney, John, Krupinski, Jerzy, Kumar, Patricia, Kumar, Shant and Slevin, Mark (2003) Changes in gene regulation and associated protein expression after acute ischaemic stroke in man. In: 17th national meeting of the British Neuroscience Association, 13-16 April 2003, Harrogate, UK.
Other
Slevin, Mark, Krupinski, Jerzy, Kumar, Patricia, Gaffney, John and Kumar, Shant (2004) Hyaluronan, angiogenesis and malignant disease. John Wiley.
Parker, Craig J., Shawcross, Susan G., Hart, Ian R., Kumar, Shant, MacKie, Rhona M., Sisely, Karen and Kumar, Patricia (2001) Expression of PAX3 spliced transcripts in human tumours of neural crest origin. Nature Publishing Group.