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Campylobacter jejuni multilocus sequence types in humans, northwest England, 2003-2004

Fox, Andrew J. and Sopwith, Will and Birtles, Andrew and Matthews, Margaret (2006) Campylobacter jejuni multilocus sequence types in humans, northwest England, 2003-2004. ISSN 1080-6040

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Abstract

Detailed understanding of the epidemiology of Campylobacter is increasingly facilitated through use of universal and reproducible techniques for accurate strain differentiation and subtyping. Multilocus sequence typing (MLST) enables discriminatory subtyping and grouping of isolate types into genetically related clonal complexes; it also has the advantage of ease of application and repeatability. Recent studies suggest that a measure of host association may be distinguishable with this system. We describe the first continuous population-based survey to investigate the potential of MLST to resolve questions of campylobacteriosis epidemiology. We demonstrate the ability of MLST to identify variations in the epidemiology of campylobacteriosis between distinct populations and describe the distribution of key subtypes of interest.

Item Type: Article
Additional Information: Full-text of this article is not available in this e-prints service. This article was originally published [following peer-review] in Emerging Infectious Diseases, published by and copyright U.S. Department of Health and Human Services.
Divisions: Faculties > Faculty of Science and Engineering > Department of Biological Sciences
Date Deposited: 25 Jan 2010 16:16
Last Modified: 01 Sep 2016 13:57
URI: http://e-space.mmu.ac.uk/id/eprint/90569

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